Micovalosin
It’s Granules for preparation of oral Solution, Cream Colored granules dissolved in water.
Composition:
1gm of preparation contains the active ingredient, Tylvalosin Tartrate-625mg
PHARMACOLOGICAL PROPERTIES:
This is an antibiotic of the new generation macrolide group, highly active in relation to gram-positive (Staphylococcus spp., Clostridium spp., Enterococcus spp, Brachyspira hyodysenteriae.) and gram-negative microorganisms (Lawsonia intracellularis, Brachyspira hyodysenteriae, Brachyspira pilosicoli, Ornithobacterium rhinotracheale).
The following mycoplasmas are particularly sensitive to Micovalosin: (Mycoplasma gallisepticum, Mycoplasma hyopneumoniae, Mycoplasma synoviae, Mycoplasma meleagridis, Mycoplasma agalactiae, Mycoplasma bovigenitalium).
Micovalosin is quickly absorbed after oral use. 2 and 12 hours after use of the recommended dose, a concentration of 0.060-0.066 mg/ml can be observed. It’s quickly distributed in tissues with the highest concentrations in the lungs, bile, intestinal mucosa, spleen, kidneys and liver.
There is confirmation that the concentration of macrolides is higher in the place of infection than in the plasma, especially in neutrophils, alveolar macrophages and alveolar epithelial cells. Study of the metabolism in vitro confirmed that Tylvalosin metabolites to 3-O acetylation. It is removed from the body via urine and bile.
APPLICATION:
Treatment of pigs suffering from enzootic pneumonia, proliferative enteropathy (ileitis) and dysentery, caused by the microorganisms (Mycoplasma hyopneumoniae, Brachyspira hyodysenteriae, Lawsonia intracellularis), sensitive to this medicine.
Treatment of poultry (chickens, turkeys) and pheasants, suffering from mycoplasmosis, ornithobacteriosis, clostriosis and other bacterial infections caused by microorganisms sensitive to Tylvalosin.
DOSAGE:
Orally in drinking water in doses
Pigs – 5mg of Micovalosin for 1kg of body weight of an animal every twenty-four hours over the course of 5 days.
The amount of the drug needed for treatment is calculated using the formula:
The quantity of the drug in grams = the total amount of body weight of pigs subject to treatment in kg x 5/625.
Chickens, pheasants – 25mg Micovalosin for 1kg of body weight of a bird every twenty-four hours over the course of 3 days.
Turkeys – 25mg Micovalosin for 1kg of body weight of a bird every twenty-four hours over the course of 5 days.
WITHDRAWAL PERIOD:
Slaughter of animals for meat is permitted twenty-four hours (pigs) and forty-eight hours (birds) after the last use of the drug. Meat obtained outside this term is utilized or fed to unproductive animals, depending on the conclusion of a veterinary practitioner Chicken eggs can be used in food without restrictions
FORM OF ISSUE:
A packet with aluminum foil laminated for 400g.
STORAGE:
A dry, dark place out of reach of children, with a temperature of from 15 °C to 25 °C.
Use by date – 2 years.
Use by date after initial opening of primary packaging – 5 weeks.
Use by date after adding to drinking water: 24 hours.
For use in veterinary medicine!